HIGHLIGHTS
- who: Toma Tebaldi from the (UNIVERSITY) have published the article: Whole-genome cartography of p53 response elements ranked on transactivation potential, in the Journal: (JOURNAL)
- what: The authors provide a comprehensive annotation of canonical and non-canonical p53 REs in the human genome ranked on predicted transactivation potential. Analysis the authors could determine that the frequency of REs in the global set of human promoters is slightly but significantly higher than the frequency of REs in scrambled sequences (Fig 2b). The authors propose DNAJA1, MAP2K3 and potentially YAP1 as new direct p53 target genes, although . . .
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