HIGHLIGHTS
- who: Top from the Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA have published the research work: MAPK activation and HRAS mutation identified in pituitary, in the Journal: (JOURNAL)
- what: The authors report novel genetic mutations that may provide additional insights into the future treatment of this disease.
SUMMARY
The authors performed whole exome next-generation sequencing on each SCO case, using matched DNA as control. Among the mutations present, samples 3A and 3B both showed a Q61R mutation in the Harvey rat sarcoma viral oncogene homolog (HRAS . . .
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