Dominant negative effects by inactive spa47 mutants inhibit t3ss function and shigella virulence

HIGHLIGHTS

  • who: Jamie L. Burgess and colleagues from the Department of Chemistry and Biochemistry, Utah State University, Logan, Utah, United States of America have published the research work: Dominant negative effects by inactive Spa47 mutants inhibit T3SS function and Shigella virulence, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0228227]. January 24, 2020 of October/15,/2019
  • what: The authors provide both in vitro and in vivo characterization of Spa47 oligomerization and activation in the presence and absence of engineered ATPase-inactive Spa47 mutants. The ability of S. flexneri strains used in . . .

     

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