A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by imp: possible implications for the disease pmm2-cdg

HIGHLIGHTS

• who: Valentina Citro and colleagues from the Campania "Luigi Vanvitelli", Caserta, Italy have published the Article: A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP: Possible implications for the disease PMM2-CDG, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0189629]. December 19, 2017 of July/26,/2017
• what: Using 31P-NMR the authors could demonstrate that PMM1 as well as PMM2 convert Man-6-P into Man-1-P, this activity had never been monitored directly before.
• how: A similar result was obtained . . .
  

   

  

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