Organic anion transporting polypeptides oatp1b1 and oatp1b3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene

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  • who: Raloxifene et al. from the were followed in the University Medical Centre (Maribor, Slovenia)Four patients were removed from the study due to not following the study protocol. At baseline, blood was drawn for measurements of lipids, bone turnover markers and DNA extraction. All investigations were carried out at , a.m. after an overnight fast. After the first visit, the participants started with raloxifene , mg, cholecalciferol , I.U. and calcium carbonate , mg daily. Patients did not get any dietary advice. Compliance was checked orally at the regular check-ups by a physician three times during the . . .

     

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