Cxc receptor-4 mrna silencing abrogates cxcl12- induced migration of colorectal cancer cells

HIGHLIGHTS

  • who: Claudia Rubie and collaborators from the (UNIVERSITY) have published the paper: CXC receptor-4 mRNA silencing abrogates CXCL12- induced migration of colorectal cancer cells, in the Journal: (JOURNAL)
  • what: The aim of this study was to conduct a comparative CXCL12/CXCR4 expression analysis and to investigate the functional role of CXCR4 in metastatic and non-metastatic CRC derived cell lines.
  • how: A detailed overview of siRNA control experiments is presented in Table 2. The results are well in line with recent findings demonstrating a role of CXCL12 in promoting cell migration and . . .

     

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