Immune cell extracellular vesicles and their mitochondrial content decline with ageing

HIGHLIGHTS

• who: Xin Zhang from the (UNIVERSITY) have published the research: Immune cell extracellular vesicles and their mitochondrial content decline with ageing, in the Journal: (JOURNAL)
• what: As shown here, high resolution multicolor flow cytometry is a powerful technique that simultaneously measures plasma EV size, surface markers and cargo that may reflect biological processes of specific cell types and indicate an ageing phenotype.
• how: Functional mitochondrial activity was highest in LEV and the CD34+ HSC-associated EVs With carbocyanine-based MitoTracker Deep Red FM dye that stains respiring mitochondria in live cells the authors . . .
  

   

  

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