Adaptation of hepatitis c virus to mouse cd81 permits infection of mouse cells in the absence of human entry factors

HIGHLIGHTS

• who: Zeisel and colleagues from the Mathematical Modeling, Johann Wolfgang Goethe-University, Frankfurt, Germany, Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical have published the research work: Adaptation of Hepatitis C Virus to Mouse CD81 Permits Infection of Mouse Cells in the Absence of Human Entry Factors, in the Journal: (JOURNAL) of January/29,/2010
• what: The authors show that HCV J6-derived glycoproteins adapted to mouse CD81 permit infection of mouse cells in the absence of human factors.
• how: Funding This work was supported by an Emmy Noether-fellowship (PI 734/1 . . .
  

   

  

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