Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show aldh cd44 phenotype and sphere-forming capacity

HIGHLIGHTS

  • who: Cortes-Dericks et_al BMC Cancer and colleagues from the (UNIVERSITY) have published the article: Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH CD44 phenotype and sphere-forming capacity, in the Journal: (JOURNAL)
  • what: The study shows that ALDHhigh CD44+ cells are implicated in conveying tolerance to cisplatin in the three MPM cell lines.
  • how: FACS data were analysed with Flowjo software 7.2.5 (Treestar Oregon USA). The data showed that all of the MPM cell lines contained sphere-forming cells with the ability to produce spheres up to . . .

     

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