HIGHLIGHTS
- who: N. O. Alieva from the Mechanobiology InstituteNational University have published the paper: Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors demonstrate that adhesion of filopodia to fibronectin strongly depends on myosin IIA activity. The authors focused on filopodia originating from cell edges and extending along the fibronectin-coated substrate. The authors demonstrate that proper adhesion of filopodia can be prevented not only by inhibition of myosin II or formin, but also by micro-environmental conditions under which filopodia tips do not develop traction . . .
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