Tp53 germline mutations in the context of families with hereditary breast and ovarian cancer: a clinical challenge

HIGHLIGHTS

• who: Sabine Grill from the Department of Gynecology and Obstetrics, University Hospital Klinikum Rechts der Isar, Technical University Munich (TUM), Munich, Germany have published the research: TP53 germline mutations in the context of families with hereditary breast and ovarian cancer: a clinical challenge, in the Journal: (JOURNAL)
• what: Emphasizing the lack of consensus about clinical implications the authors aim to further characterize TP53g mutations in HBOC families. The authors examined a cohort of 1876 HBC/ HBOC index patients who were counseled and referred for genetic testing at the Department of Gynecology and Classic LFS criteria . . .
  

   

  

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