T-cell responses to immunodominant listeria epitopes limit vaccine-directed responses to the colorectal cancer antigen, guanylyl cyclase c

HIGHLIGHTS

• who: John C. FlickingerJr from the Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States have published the research: T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C, in the Journal: (JOURNAL)
• what: The project was conceptualized, data were reviewed, and the manuscript was reviewed and edited by all authors.

SUMMARY

In this context, there has been renewed interest in utilizing cancer vaccines as agents that expand tumor-specific T_cells and promote T-cell infiltration into tumor . . .

 



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