High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity

HIGHLIGHTS

  • who: Juan Liu from the (UNIVERSITY) have published the research work: High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity, in the Journal: (JOURNAL) of 15/02/2022
  • what: This is one of the many challenges in drug research and development, and also the main reason for the failure of pharmaceutical enterprises and the misfortune of patients . This work provides the first systematic in_vitro study of the mechanisms involved in DLX-DILI in human liver, using extracellular liver matrix bioactivated HepaRG spheroids.
  • how: All experiments were carried . . .

     

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