Synthesis of 3,4-dihydropyrimidin(thio)one containing scaffold: biginelli-like reactions

HIGHLIGHTS

  • who: Francisco Sánchez-Sancho and collaborators from the Departamento Química Orgánica, University of Valencia, Avda Vicente Andrés Estellés s/n have published the article: Synthesis of 3,4-Dihydropyrimidin(thio)one Containing Scaffold: Biginelli-like Reactions, in the Journal: Pharmaceuticals 2022, 948 of 30/07/2022
  • what: __SECTION__ 8. Conclusions.
  • how: The best results were obtained with urea or thiourea under solvent-free conditions .13-dicarbonyl The spiro were tested for their ureaseagainst inhibitory 15 of 65 bean urease . activity against Jack bean urease .

SUMMARY

     

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