Dna methylation in glioblastoma: impact on gene expression and clinical outcome

HIGHLIGHTS

• who: Etcheverry et_al BMC Genomics and colleagues from the The prospective cohort included , patients with newly diagnosed GBM (World Health Organization (WHO) grade IV), admitted to the Neurosurgery Departments of Rennes and Angers University HospitalsTumor samples were collected, following informed consent, in accordance with the French regulations and the Helsinki Declaration. Initial histologic findings were confirmed, according to the WHO classification [22], by a central review panel including at least two neuropathologists. The male/female ratio was, :0.96. Median age at diagnosis was, ., ± , years (range: , , years) and median preoperative Karnofsky Performance Status (KPS) was, ., (range: , , ). Fifty . . .
  

   

  

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