HIGHLIGHTS
- who: Ting Li et al. from the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College have published the research work: Novel Complex of PD-L1 Aptamer and Holliday Junction Enhances Antitumor Efficacy in Vivo, in the Journal: Molecules 2021, 26, 1067. of /2021/
- what: The authors designed a DNA nanostructure that had four PD-L1 aptamers built into it.
- how: The results indicated that phosphorothioate modification could significantly improve nuclease resistance and serum stability and possibly prolong the circulation time of Apt-HJ. The results indicated . . .
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