Combined inhibition of polo-like kinase-1 and wee1 as a new therapeutic strategy to induce apoptotic cell death in neoplastic mast cells

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• who: Manuela Mancini et al. from the obtained by transfecting CD34+ umbilical cord blood cells with KIT WT or mutant (D V) were cultured in KIT ligand stem cell factor (SCF)-containing medium or in SCF free medium (IMDM supplemented with, % penicillin/streptomycin, % sodium pyruvate, % MEM vitamins, % MEM non-essential amino acids, % of, glutamine, % commercial solution of insulin transferrin-sodium selenite, % bovine serum albumin, all purchased by GIBCO), respectively. These were kindly provided by Prof. Michel Arock (Department of Hematological Biology, Pitié-Salpêtrière Hospital, Pierre et Marie Curie University, Paris). Moreover, D and Ba, cell . . .
  

   

  

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