Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

HIGHLIGHTS

  • who: Annah B. Wyss from the Iceland United States have published the paper: Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 11/Oct/2017
  • how: Although few ancestry-specific eQTL datasets exist the authors identified two such studies with blood samples from African American participants SAPPHIRE (N=597) and MESA (N=233)36. For functional annotation the authors considered all novel variants with P and amplt 5 × 10-8 from the 60 loci discovered in the ancestry -specific and multiethnic meta-analyses . . .

     

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