Overexpression of mitochondrial ligases reverses rotenone-induced effects in a drosophila model of parkinson’s disease

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  • who: Elzbieta Pyza from the Department of Cell Biology and Imaging, Institute of Zoology and Biomedical Research, Jagiellonian University, Kraków, Poland have published the research work: Overexpression of Mitochondrial Ligases Reverses Rotenone-Induced Effects in a Drosophila Model of Parkinson's Disease, in the Journal: (JOURNAL)
  • what: The authors examined whether the strong expression of two major mitochondrial ligases may protect flies exposed to rotenone, against developing symptoms typical of Parkinson's disease. The authors showed that exposure to 500 µM rotenone in Drosophila (Coulom and Birman, 2004) reduces the levels of Atg5 and . . .

     

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