Extracellular vesicles from a23187-treated neutrophils cause cgas-sting-dependent il-6 production by macrophages

HIGHLIGHTS

  • who: Edwina R. Allen from the The University of Sydney, Australia have published the Article: Extracellular vesicles from A23187-treated neutrophils cause cGAS-STING-dependent IL-6 production by macrophages, in the Journal: (JOURNAL)
  • future: EVs vary depending on agonists used and while additional studies are needed to characterize S. aureus-EVs and other EVs produced during infection the authors continued to focus on A23187-EVs and their associated DNA which lack bacteria and bacteriaassociated molecules that might also activate pattern_recognition receptors. when macrophages were treated with spontaneous-EVs for the same time period .
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