Cytoprotective effect of genistein against dexamethasone-induced pancreatic β-cell apoptosis

HIGHLIGHTS

  • who: Kanchana Suksri from the DivisionMahidol University have published the paper: Cytoprotective effect of genistein against dexamethasone-induced pancreatic β-cell apoptosis, in the Journal: Scientific Reports Scientific Reports
  • how: The results showed that both nuclear and membrane ER inhibitors diminished the protective effect of genistein against dexamethasone. Optical absorption at 450 nm was measured and the acquired data were analyzed.

SUMMARY

    To examine the effects of dexamethasone and genistein on pancreatic β-cells, INS-1 cells were cultured with either 0.1 µM of dexamethasone, 10 μM of genistein, or the combination . . .

     

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