HIGHLIGHTS
- who: Zhen Li from the Department of Anesthesiology and Pain Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China have published the paper: SCFAs Ameliorate Chronic Postsurgical Pain-Related Cognition Dysfunction via the ACSS2-HDAC2 Axis in Rats, in the Journal: (JOURNAL)
- what: The authors report that chronic postsurgical pain causes cognitive behavioral deficits in rats, the gut SCFA-producing microbiome mediates pain-related cognitive impairments, and_(3) SCFA consumption alleviates chronic postsurgical pain-induced cognitive deficits by improving histone acetylation and synaptic transmission via the ACSS2-HDAC2 . . .
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