Vav2 is a novel app-interacting protein that regulates app protein level

HIGHLIGHTS

• who: Youjia Zhang from the Laboratory University of Jinan, China have published the paper: Vav2 is a novel APP-interacting protein that regulates APP protein level, in the Journal: Scientific Reports Scientific Reports
• what: The authors have identified that Vav2 is a novel APP-interacting protein.
• how: As expected the results showed that A ­ PPswY682A abolish its binding to Vav2-SH2 (Fig 4B). Taken together these results indicated that Vav2 can interact with APP through its SH2 domain in mammalian cells. | 1212752 | 3 Vol.(0123456789) Overexpression of Vav2 markedly increases APP protein level . . .
  

   

  

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