Androgen-induced mig6 regulates phosphorylation of retinoblastoma protein and akt to counteract non-genomic ar signaling in prostate cancer cells

HIGHLIGHTS

  • who: Tim Schomann and collaborators from the Institute of Human Genetics, Jena University Hospital, Am Klinikum, Jena, Germany have published the article: Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells, in the Journal: Biomolecules 2022, 12, x FOR PEER REVIEW of 20/01/2022
  • what: SAL treatment induces cellular senescence in PCa cells.
  • how: Similar results were obtained using dihydrotestosterone .

SUMMARY

    Consistently, it was discovered that treatment with 1 pM R1881, defined as low androgen levels (LAL . . .

     

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