Transforming growth factor-β1 protects against lpc-induced cognitive deficit by attenuating pyroptosis of microglia via nf-κb/erk1/2 pathways

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  • who: Yi Xie from the Huazhong University of Science and Technology, Wuhan, China have published the article: Transforming growth factor-β1 protects against LPC-induced cognitive deficit by attenuating pyroptosis of microglia via NF-κB/ERK1/2 pathways, in the Journal: (JOURNAL)
  • what: The studies demonstrated notably relieved the demyelinating injury and disorder in LPC-modeling mice by attenuating the inflammatory of via ERK1/2 and NF-κB pathways. The authors proposed and verified that administration of TGF-β1 could evidently alleviate the demyelinating severity, microglial activation, and accompanied cognitive deficit in LPC-induced demyelinating . . .

     

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