Molecular mechanisms and functions of pyroptosis in sepsis and sepsis-associated organ dysfunction

HIGHLIGHTS

  • who: Ri Wen from the Washington State University, United States have published the research work: Molecular mechanisms and functions of pyroptosis in sepsis and sepsis-associated organ dysfunction, in the Journal: (JOURNAL)
  • what: The studies discussed in this review strongly demonstrate that pyroptosis and its related pathways play critical roles in sepsis and SAOD, although many questions remain unsolved. The studies described herein provide strong evidence that pyroptosis plays an important role in sepsis; however, the detailed molecular mechanisms of pyroptosis are not well understood.
  • how: The results showed that the activation of . . .

     

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