Identification of the antibacterial action mechanism of diterpenoids through transcriptome profiling

HIGHLIGHTS

  • who: Aralia continentalis et al. from the United States Tufts United States have published the article: Identification of the antibacterial action mechanism of diterpenoids through transcriptome profiling, in the Journal: (JOURNAL)
  • what: Three types of diterpenoids, AA, CA, and KA were extracted from A. continentalis.
  • how: The transcriptome data showed that S. mutans possibly upregulates both genes that synthesize WTAs and RGPs to counteract the antimicrobial activity of diterpenoids.

SUMMARY

    It has been used for its anti-inflammatory, anti-diabetic, anti-cancer, and antimicrobial activity in therapeutics (Lim et_al . . .

     

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