HIGHLIGHTS
- who: Laurent R. Gauthier from the Université have published the paper: The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation, in the Journal: Scientific Reports Scientific Reports of 18/Oct/2019
- what: The authors report that sublethal doses of irradiation enhance the motility and invasiveness of human GSCs through HIF1α nuclear accumulation that in turn increases the cytoplasmic actin nucleator JMY. The study shows that the key factor linking the radiation-induced enhancement of GSCs to stem-like properties is the fact that GSCs are much more prone than differentiated cells to . . .
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