HIGHLIGHTS
- who: Alex de Mendoza from the Harry Perkins Institute Research, The University, Australia have published the Article: Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability, in the Journal: (JOURNAL)
- what: The authors demonstrate that induced can exist simultaneously on nucleosomes that possess the active histone modification H3K4me3 or bound by the initiated form of RNA polymerase II. The authors show that the simultaneous methylation of thousands of promoters in the human genome frequently resulted in no detectable repression of gene_expression. The authors provide a list of promoters that are . . .
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