Hiv promoter integration site primarily modulates transcriptional burst size rather than frequency

HIGHLIGHTS

  • who: HIV Promoter Integration Site and colleagues from the California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California, United States of America, Department of Chemical Engineering have published the paper: HIV Promoter Integration Site Primarily Modulates Transcriptional Burst Size Rather Than Frequency, in the Journal: (JOURNAL) of September/30,/2010
  • what: The authors assess the context dependence of expression heterogeneity from diverse single integrations of a HIV-promoter/GFP-reporter cassette in Jurkat T-cells. The authors propose several qualitative models that may explain this inferred variation of transcriptional dynamics with genomic environment . . .

     

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