HIGHLIGHTS
- who: Hugh from the University, Bethlehem, PA, USA have published the Article: Regulated Assembly of the Mitotic Spindle: A Perspective from Two Ends, in the Journal: (JOURNAL)
- what: Since microtubule assembly begins at the centrosome, in the next section the authors discuss how centrosomes contribute to spindle assembly.
SUMMARY
Defects in the number of centrosomes have been observed in a number of human tumors, including cells from the early stages of tumor development (Pihan et_al, 2001; Lingle et_al, 2002; D'Assoro et_al, 2002). Likewise, defects in KLP38B function or KLP38B depletion . . .
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