HIGHLIGHTS
- who: Seong-Jun Kim and colleagues from the Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, California, United States of America have published the research: Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy, in the Journal: (JOURNAL) of March/28,/2013
- what: The authors investigated the involvement of mitophagy in HCV-infected cells. The authors demonstrate that Parkindependent mitophagy is directly associated with HCVmediated decline in oxidative_phosphorylation. For the first time, the authors demonstrate that HCV induces organelle selective autophagic degradation of mitochondria (mitophagy).
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