HIGHLIGHTS
- who: Matti Vornanen from the Department of Biology, University of Eastern Finland, Joensuu, Finland have published the paper: Tetrodotoxin Sensitivity of the Vertebrate Cardiac Na+ Current, in the Journal: (JOURNAL)
- what: The present electrophysiological findings suggest that the cardiac phenotype of INa is TTX-sensitive in fishes, frogs and birds, and TTX-resistant in mammals and at least in some reptiles.
SUMMARY
Opening of the voltage-sensitive Na+ channels (Nav) depolarizes plasma_membrane and causes a rapid impulse spread in excitable cells via abrupt Na+ influx. In most cases, TTX-resistance is . . .
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