Pharmacokinetic boosting of osimertinib with cobicistat in patients with non-small cell lung cancer: the osiboost trial

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  • who: Ard van Veelen from the (1) Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center+, POBOX , AZ, Maastricht, the Netherlands have published the research: Pharmacokinetic boosting of osimertinib with cobicistat in patients with non-small cell lung cancer: the OSIBOOST trial, in the Journal: (JOURNAL)
  • what: In this study, the boosting capacity of cobicistat on osimertinib exposure was evaluated in patients with NSCLC who had a low osimertinib plasma trough concentration, i.e. ≤195 ng/mL. 15 Future research could therefore also focus on evaluating whether the approach presented in this study could . . .

     

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