A cell double-barcoding system for quantitative evaluation of primary tumors and metastasis in animals that uncovers clonal-specific anti-cancer drug effects

HIGHLIGHTS

• who: Arkadi Hesin and collaborators from the All animals were housed under pathogen-free conditions, and all animal procedures were approved by Ariel University Institutional Animal Care and Use CommitteeCell line suspensions were prepared in, :, matrigel (ECM Gel #E1270, Sigma-Aldrich) and approximately, ., × , cells were subcutaneously injected into the flanks of, week-old female nude (Nu/Nu) mice (Envigo, Ness Ziona, Israel). Tumors were measured with calipers and the tumor volume was calculated according to the formula Vol=0., × L ×, . When tumors reached the volume of approximately, mm3, mice were randomly assigned into either treatment group or . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.