Tie-2 signaling activation by angiopoietin 2 on myeloid-derived suppressor cells promotes melanoma-specific t-cell inhibition

HIGHLIGHTS

• who: Amélie Marguier from the France, Department of Dermatology, University Hospital of, France have published the article: TIE-2 Signaling Activation by Angiopoietin 2 On Myeloid-Derived Suppressor Cells Promotes Melanoma-Specific T-cell Inhibition, in the Journal: (JOURNAL) of 29/04/2022
• what: The authors investigated the features and immune suppressive function of a novel subset of monocytic MDSC overexpressing TIE-2 (TIE-2+ M-MDSC) the receptor for the pro-angiogenic factor 2 (ANGPT2). The authors investigated the TIE-2+ M-MDSC in patients with melanoma and their suppressive function against tumorspecific . . .
  

   

  

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