HIGHLIGHTS
- who: Structural Biology and collaborators from the Division of Biological Chemistry and Molecular University of Dundee, Dundee , EH have published the article: A preliminary crystallographic analysis of the putative mevalonate diphosphate decarboxylase from Trypanosoma brucei, in the Journal: (JOURNAL) of 19/04/2005
SUMMARY
The enzymes of the mevalonate (MVA) pathway of isoprenoid precursor biosynthesis represent potential drug_targets in trypanosomes since active sterol biosynthesis has been shown to be essential for growth and survival in T. cruzi (Urbina, 1997, 2002). Several MVA-pathway enzymes, including MDD, have been shown to be essential in . . .
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