Hydrogels embedded with melittin and tobramycin are effective against pseudomonas aeruginosa biofilms in an animal wound model

HIGHLIGHTS

  • who: Christopher M. Waters from the Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, United States, The have published the research: Hydrogels Embedded With Melittin and Tobramycin Are Effective Against Pseudomonas aeruginosa Biofilms in an Animal Wound Model, in the Journal: (JOURNAL)
  • how: The authors evaluated melittin for activity in combination with aminoglycosides against mature biofilms formed by P. aeruginosa. The authors developed a novel hydrogel formulation embedded with melittin and/or tobramycin and only observed significant killing of P. aeruginosa biofilms in a murine wound model after 4-h of . . .

     

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