C-myc-induced aberrant dna synthesis and activation of dna damage response in p300 knockdown cells*

HIGHLIGHTS

  • who: Natesan Sankar from the Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois , have published the research work: c-Myc-induced Aberrant DNA Synthesis and Activation of DNA Damage Response in p300 Knockdown Cells*, in the Journal: (JOURNAL) of MAY/29,/2009
  • what: This observation also consistent with other results presented this paper which suggest that large number of replication origins p300-depleted cells they might be accumulating as hypofunctional origins. this paper studied effects of forced activation human cells on replication when levels reduced. In parallel with the experiment described . . .

     

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