Alternative splicing of nurf301 generates distinct nurf chromatin remodeling complexes with altered modified histone binding specificities

HIGHLIGHTS

  • who: So Yeon Kwon and colleagues from the Institute of Biomedical Research, University of Birmingham, Edgbaston, United Kingdom, Laboratory of Biochemistry and Molecular Biology, National Cancer Institute have published the research: Alternative Splicing of NURF301 Generates Distinct NURF Chromatin Remodeling Complexes with Altered Modified Histone Binding Specificities, in the Journal: (JOURNAL) of July/24,/2009
  • what: The authors demonstrate that three NURF301 isoforms are expressed and that these encode functionally distinct NURF chromatin remodeling complexes. By comparing microarray expression profiles and phenotypes of null Nurf301 mutants with mutants that remove the C-terminal PHD fingers . . .

     

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