Mechanism of aaa+ atpase-mediated ruvab-holliday junction branch migration

HIGHLIGHTS

  • who: Jiri Wald from the (UNIVERSITY) have published the Article: Mechanism of AAA+ ATPase-mediated RuvAB-Holliday junction branch migration, in the Journal: (JOURNAL) of 19/08/2021
  • what: The authors show that RuvB motors rotate together with the DNA substrate, which, together with a progressing nucleotide cycle, forms the mechanistic basis for DNA recombination by continuous branch_migration. The authors show that RuvB motors translocate the DNA as molecular levers in an ATP-dependent power stroke to convert chemical energy to mechanical force.
  • how: This analysis revealed a low average r.m.s . . .

     

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