Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models

HIGHLIGHTS

• who: Emilia J. Berthold from the Drexel University, United States have published the paper: Effects of immunophilin inhibitors and non-immunosuppressive analogs on coronavirus replication in human infection models, in the Journal: (JOURNAL)
• what: The authors assessed the anti-coronaviral potential of CsA, FK506, and non-immunosuppressive analogs of both in an organotypic model of the bronchial epithelium as well as in other frequently used human models of coronavirus infection.
• how: For the infection of Huh-7.5 the authors used Renilla luciferaseexpressing HCoV-229E-RLuc at an MOI of 0.1 largely . . .
  

   

  

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