HIGHLIGHTS
- who: Carmen Mota Reyes and colleagues from the Department of Surgery, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany have published the research: Regulatory T Cells in Pancreatic Cancer: Of Mice and Men, in the Journal: Cancers 2022, 14, 4582. of /2022/
SUMMARY
The major contributors to the pro-tumorigenic features of the pancreatic tumor microenvironment include a strongly fibrotic stroma and an accumulation of immunosuppressive cell populations such as regulatory T_cells (Tregs), tumor-associated macrophages (TAMs) and MDSC. Treg Cells Treg cells, defined as CD4+ CD25+ Foxp3 . . .
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