Activity-regulated e3 ubiquitin ligase trim47 modulates excitatory synapse development

HIGHLIGHTS

  • who: Sourav Banerjee from the Scientific Research, India have published the Article: Activity-regulated E3 ubiquitin ligase TRIM47 modulates excitatory synapse development, in the Journal: (JOURNAL)
  • what: The study demonstrated that TRIM47 is localized in neuronal dendrites and synapses of developing hippocampal neurons.

SUMMARY

    Synapses are formed in the developing as well as in the adult brain while performing cognitive functions (Cohen-Cory, 2002; Zito and Svoboda, 2002; Cornelia Koeberle et_al, 2017; Nguyen et_al, 2020). The density of synapses gradually increases from P7 to P15 and reaches a peak at P21 . . .

     

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