Pki-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting the pi3k/akt/mtor pathways and dna damage repair

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  • who: Yinghai Xie et al. from the First People`s Hospital and First Hospital of School, Anhui of Science Technology, China have published the article: PKI-587 Enhances Radiosensitization of Hepatocellular Carcinoma by Inhibiting the PI3K/AKT/mTOR Pathways and DNA Damage Repair, in the Journal: PLOS ONE of 17/06/2021
  • what: The authors evaluated the role of the dual PI3K/mTOR inhibitor PKI-587 on radiosensitization of HCC and its possible mechanism. The research has confirmed that PKI-587, when combined with radiation, can block the abnormal activation of PI3K/AKT/mTOR induced . . .

     

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