HIGHLIGHTS
- who: Y Ci from the State Key Laboratory Medical Sciences, Beijing, China have published the research: ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells, in the Journal: (JOURNAL)
- what: This study shows that phospho-p53 (Ser392) binds to the promoter of ULK1, suggesting that p53 may regulate the transcription of ULK1.
- how: After labelling with DCF flow cytometry was used to analyse the ROS level of NB4 cells and results showed that selenite induced the increase of ROS. Data showed that c-PARP (cleaved . . .
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