HIGHLIGHTS
- who: Shinwan Kany and collaborators from the Department of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, Frankfurt, Germany have published the research: Reduced NLRP3 Gene Expression Limits the IL-1 β Cleavage via Inflammasome in Monocytes from Severely Injured Trauma Patients, in the Journal: Mediators of Inflammation of 23/01/2018
- what: This study shows that CD14+ monocytes from TP are significantly diminished in their function and that the presence of NLRP3 components is necessary in recovering the ability of monocytes to produce active IL-1β. The authors examined if the NLRP3 inflammasome in monocytes . . .
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