The yeast pif1 helicase prevents genomic instability caused by g-quadruplex-forming ceb1 sequences in vivo

HIGHLIGHTS

  • who: Vivo et al. from the Biology, Princeton University, Princeton, New Jersey, United States of America, Laboratoire de Biophysique, Museum National d'Histoire Naturelle USM, INSERM have published the Article: The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo, in the Journal: (JOURNAL) of January/12,/2009
  • what: The authors provide evidence for a new Pif1 function by demonstrating that its absence promotes genetic instability of alleles of the G-rich human minisatellite CEB1 inserted in the Saccharomyces cerevisiae genome but not of other tandem repeats. In vitro . . .

     

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