Major vault protein suppresses obesity and atherosclerosis through inhibiting ikk⠍nf-κb signaling mediated inflammation

HIGHLIGHTS

  • who: Jingjing Ben from the Laboratory Medical University, Nanjing, China have published the research: Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK⠍NF-κB signaling mediated inflammation, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors investigate the role of MVP in metabolic inflammation. The authors have provided a critical proof | https://doi.org/10.1038/s41467-019-09588-x of principle that MVP, the major component of vaults, may act as an intrinsic inflammatory gatekeeper in macrophages to regulate obesity-associated metabolic disorders and atherosclerosis. The authors provide evidence to show . . .

     

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