Phosphoglucose isomerase is important for aspergillus fumigatus cell wall biogenesis

HIGHLIGHTS

  • who: Yao Zhou et al. from the University of Dundee Guangxi Biological Sciences and Biotechnology Center, Guangxi Academy of Sciences, Nanning, Guangxi, China have published the article: Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis, in the Journal: (JOURNAL) of 05/09/2022
  • what: This study shows that PGI is required for A. fumigatus survival and maintenance of metabolic homeostasis and possesses a potentially exploitable difference near the active_site compared to the human orthologue. Taken together, this study provides a genetic and structural basis for the development of fungal PGI inhibitors. mBio were . . .

     

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